|
Introduction
 |
Waters
manufactures its consumable chromatography products since many
years and will continue its unique status as compared to others
in the industry. Its primary mission is to synthesize high
quality chromatography supports to pack chromatography columns,
assemble solid-phase extraction devices and to produce reagent
including Symmetry Nova-Pak, uBondapak materials. |
uBondapak/Bondapak
Packings
If your method calls up for uBondapak
C18 packings, there is only one uBondapak C18 packing
material. Waters has set the standard for reproducible,
high-performance chromatographic columns. Waters uBondapak
columns are still the most widely referenced
and requested columns in the world.
Nova-Pak
Packings
The
4 µm small particle size of Nova-Pak bonded phases offers high
resolution, more efficient and faster chromatography by using
shorter columns, reducing solvent
consumption ot
by using longer columns to resolve even the most complex
mixture. Analytical columns with 4 micron particle size packing are available end fittings are available in 75, 150 and 300 mm
length. Semi-preparative columns with 6 micron particle size
packing give you an
unparalleled range of separation possibilities.
Symmetry
Packing
The
new standard of next generation HPLC assay.
Many
of today’s therapeutic compounds contains strongly basic amine
groups that are notoriously difficult to chromatograph with the
simpler, cost-effective mobile phase systems desired in a
manufacturing environment. The result is asymmetrical peaks that
deprive the HPLC system sensitivity.
Some
of the newer “base-deactivated” or “high-purity” column
packing materials can improve peak shape, but you are forced to
work exclusively at low pH, where the net charge of the silica
surface, and therefore, undesirable ion-exchange interactions,
approach zero. In chromatography, pH is one of the most powerful
tools you can use to optimize a separation of mixed analytes for
resolution and analysis time.
If you can’t vary your pH, you may have to work harder
and longer to develop methods. Symmetry columns deliver the same
superior peak shape across a broad pH range, from 2 through 7.
Shaper peaks result in more sensitive methods.
Symmetry columns give you sharp peaks at pH 2 through to
pH 7, using simple mobile phases.
The result is more sensitive, more rugged methods.
The
real test for column performance is measured over time.
Other manufacturers may claim reproducibility, but no
other column supplier controls and documents every stop of the
manufacturing process like Waters do.
A complete “Certificate of Analysis” is included with
every Symmetry Column.
Each certificate is backed by world class cGMP and ISO 90002
registered documentation trail that allows Waters (or You) to
trace the origin of any column all the way back to the results
of incoming QC tests performed on raw materials. The Symmetry
column’s “Certificate of Analysis” is the most
comprehensive in the industry, covering all key properties of
the silica, bonded phase and final chromatography.
Water
Symmetry columns are available in 3.5, 5 and 7
micron particle size material. They offer the highest
performance and reproducibility standards ever achieved.
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COLUMNS
|
DIMENSION
|
PARTICAL
|
PART
|
|
|
|
SIZE
|
NUMBER
|
|
|
|
|
|
|
u
Bondapak C 18
|
3.9x300
|
10
|
27324
|
|
u
Bondapak C 18
|
4.6x250
Cartridge
|
10
|
52860
|
|
u
Bondapak CN
|
3.9x150
|
10
|
86686
|
|
u
Bondapak NH2
|
3.9x300
|
10
|
84040
|
|
u
Bondapak Phenyl
|
3.9x300
|
10
|
27198
|
|
Novapak
C 18
|
3.9x150
|
4
|
86344
|
|
Novapak
C 18
|
3.9x300
|
4
|
11695
|
|
Novapak
C 18
|
3.9x150
Cartridge
|
4
|
36975
|
|
Novapak
C 18
|
4.6x150
Cartridge
|
4
|
52845
|
|
Novapak
C 18
|
4.6x250
Cartridge
|
4
|
52840
|
|
Novapak
C 8
|
3.9x150
|
4
|
35876
|
|
Novapak
C 8
|
3.9x150
Cartridge
|
4
|
36985
|
|
Novapak
C 8
|
4.6x150
Cartridge
|
4
|
52855
|
|
Novapak
C 8
|
4.6x250
Cartridge
|
4
|
52850
|
|
Novapak
Phenyl
|
3.9x150
|
4
|
10656
|
|
Novapak
Phenyl
|
3.9x150
Cartridge
|
4
|
96970
|
|
Novapak
Cyano
|
3.9x150
|
4
|
44245
|
|
Novapak
Cyano
|
3.9x300
|
4
|
56920
|
|
Novapak
Cyano
|
3.9x150
Cartridge
|
4
|
44243
|
|
Novapak
Cyano
|
4.6x150
Cartridge
|
4
|
44455
|
|
Novapak
Cyano
|
4.6x250
Cartridge
|
4
|
44460
|
|
Novapak
Silica
|
3.9x150
|
4
|
10025
|
|
Symmetry
C 18
|
3.9x150
|
5
|
46980
|
|
Symmetry
C 18
|
4.6x150
|
5
|
45905
|
|
Symmetry
C 18
|
4.6x250
|
5
|
54275
|
|
Symmetry
C 18
|
4.6x250
Cartridge
|
5
|
54215
|
|
Symmetry
C 8
|
3.9x150
|
5
|
46970
|
|
Symmetry
C 8
|
4.6x150
|
5
|
45955
|
|
Symmetry
C 8
|
4.6x250
|
5
|
54270
|
|
Symmetry
C 8
|
4.6x250
Cartridge
|
5
|
54245
|
|
Spnerisorb
S-5
|
|
|
|
|
ODS-2
|
4.6x250
|
5
|
PSS
8319
|
|
ODS-1
|
4.6x250
|
5
|
PSS
8306
|
|
C-6
|
4.6x250
|
5
|
PSS
8310
|
|
C-6
|
4.6x250
|
5
|
PSS
8318
|
|
C-1
|
4.6x250
|
5
|
PSS
8326
|
|
NH2
|
4.6x250
|
5
|
PSS
8311
|
|
PHENYL
|
4.6x250
|
5
|
PSS
8308
|
|
CN-NORMAL
PHASE
|
4.6x250
|
5
|
PSS
830915
|
|
CN-REVERSE
PHASE
|
4.6x250
|
5
|
PSS
830909
|
|
W-SILICA
|
4.6x250
|
5
|
PSS
830115
|
|
SCX
|
4.6x250
|
5
|
PSS
837815
|
|
SAX
|
4.6x250
|
5
|
PSS
832715
|
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